세미나안내

[2018 05 11] 특별세미나 _Ph. D Haeshin Lee (KAIST)

Polydopamine Coating and TANNylation: Mussel and Plant-inspired Biomaterial Studies

관리자 | 2018.05.10 09:31 | 조회 592


Polydopamine Coating and TANNylation: Mussel and Plant-inspired Biomaterial Studies

 

 Date: 2018. 05. 11(Fri) , 14:00 ~ 16:00

 Place: Science Building, Room.202 Multimedia Room

 Speaker: Ph. D Haeshin Lee (KAIST)

Host of a Seminar: Prof. Sei Kwang Hahn

Abstract:

 

Catecholamines are found ubiquitously in nature. Wetting-resistant, adhesive foot-pads in mussels, neurotransmitters in the brain, melanin biopigments in the skin and eyes, squid beaks, and insect cuticles are the examples. In materials science, catecholamines have recently attracted significant attentions due to the unparalleled material-independent surface functionalization properties. The most well-known material is poly(dopamine) and other derivatives such as poly(norepinephrine), chitosan-catechol and others will be introduced.

 

The first of my talk will introduce a new concept of self-sealing which is similar yet different with conventional self-healing materials. The first example is vascular self-sealing with rapid binding of intrinsic blood serum proteins to adhesive chitosan-catechol conjugate (Shin et al. Nature Mater. 2017). The second example is plant-inspired nanoparticle formulation called TANNylation. In this study, we show that the modification of protein and peptide therapeutics with tannic acid—a flavonoid found in plants that adheres to extracellular matrices, elastins and collagens—improves their ability to specifically target heart tissue (Shin et al. Nature Biomed. Eng. 2018). Via a simple intravenous injection route, now one can easily delivery protein/peptide therapeutics directly to heart tissues. Finally, biomedical applications using polydopamine surface chemistry focusing on mammalian/stem cell culture and theranostic applications will be briefly explained in this talk.

 

Dept. of MSE / BK21+






219개(1/11페이지)
세미나안내
번호 제목 글쓴이 조회 날짜
219 [2018 12 12] 정기세미나 11th 첨부파일 관리자 35 2018.12.10 09:12
218 [2018 12 05] 정기세미나 10th 첨부파일 관리자 75 2018.12.05 08:59
217 [2018 11 28] 정기세미나 9th 첨부파일 관리자 284 2018.11.26 09:36
216 [2018 11 21] 정기세미나 8th 첨부파일 관리자 347 2018.11.19 09:47
215 [2018 11 14] 정기세미나 7th 첨부파일 관리자 448 2018.11.12 09:09
214 [2018 11 08] 특별세미나 _Prof. Jongwook KIM ( 첨부파일 관리자 567 2018.11.06 09:13
213 [2018 11 07] 정기세미나 6th 첨부파일 관리자 413 2018.11.05 09:14
212 [2018 10 31] 정기세미나 5th 첨부파일 관리자 540 2018.10.26 13:41
211 [2018 10 17] 정기세미나 4th 첨부파일 관리자 620 2018.10.15 14:14
210 [2018 10 10] 정기세미나 3rd 첨부파일 관리자 592 2018.10.05 15:40
209 [2018 09 19] 정기세미나 2nd 첨부파일 관리자 875 2018.09.17 12:16
208 [2018 09 12] 정기세미나 1st 첨부파일 관리자 851 2018.09.10 09:23
207 [2018 09 05] 신소재공학과 특별세미나 관리자 767 2018.09.03 11:24
206 [2018 08 17] 특별세미나 _Prof. Taishi Takenob 첨부파일 관리자 800 2018.08.14 08:49
205 [2018 05 30] 정기세미나 13th (박찬경 교수 정년퇴임 기념 첨부파일 관리자 795 2018.05.28 09:16
204 [2018 05 23] 정기세미나 12th 첨부파일 관리자 659 2018.05.21 09:11
203 [2018 05 16] 정기세미나 11th 첨부파일 관리자 562 2018.05.14 09:37
>> [2018 05 11] 특별세미나 _Ph. D Haeshin Lee (K 첨부파일 관리자 593 2018.05.10 09:31
201 [2018 05 09] 정기세미나 10th 첨부파일 관리자 376 2018.05.08 09:07
200 [2018 05 04] 특별세미나 _Dr. Hyobin Yoo (Harv 첨부파일 관리자 500 2018.05.03 09:48